Iron, as one of the most important nutrients, plays important roles in the entire growth and development period of rice.Studies have shown that two types of mechanisms (strategy Ⅰ and Ⅱ) are involved in the absorption of iron ions in soil by rice roots, which are jointly regulated by multiple genes.A variety of genes involved in iron ion absorption and transport have been reported previously, including upstream transcription factors OsIDEF1 and OsHRZ1, bHLH transcription factors OsIRO2, OsIRO3 and OsPRI1, as well as OsIRT1 and OsVIT2 responsible for direct iron ion transport.In alkaline soil with high pH, the absorption of iron is greatly affected, the study of the absorption and transport of iron ions in rice is also beneficial to improve the salinity and alkali resistance of rice.This review first summarizes the mechanism of iron ion absorption in rice and then reviews the key genes involved.