Abstract: In order to verify the synergistic remediation effect of calcium (Ca) containing substances on farmland soil acidification and cadmium (Cd) pollution, a field experiment was conducted to study the effects of three Ca-containing substances (quicklime, limestone powder and oyster shell powder) on soil Cd content, chemical properties (pH, cation exchange capacity, exchangeable calcium, organic matter, available NPK nutrients) and Cd content in different parts of rice. The results showed that, compared with the control (CK), the application of Ca-containing materials increases soil pH by 1.17 - 1.69 units with a range increase of 17.1% - 17.8% (P<0.05), and limestone powder treatment is with the highest pH value. The exchangeable calcium content and cation exchange quantity increase by 60.2% - 171% and 16.2% - 20.0% (P<0.05) respectively, while the available state Cd content decreases by 15.79% - 21.1% (P < 0.05). Cd content in roots, stems, leaves, husks and brown rice are significantly reduced by 25.6% - 38.5%, 61.7% - 78.5%, 60.5% - 88.9%, 61.5% - 76.9% and 47.6% - 66.7%, respectively (P<0.05). The Cd content of brown rice with all treatments is lower than the limit standard (≤0.20 mg·kg⁻¹) with limestone powder the lowest value. The Cd enrichment coefficients in different parts of rice (P<0.05) are significantly reduced by all Ca treatments. Correlation analysis showed that Cd content in all parts of rice is positively correlated with soil available Cd content (P<0.01), and is negatively correlated with soil pH and cation exchange capacity (P<0.05).The application of Ca-containing substances effectively prevent soil Cd from entering the rice body and significantly reduce the Cd content in the edible part-brown rice. Limestone powder is with the best effect of Cd reduction by acid adjustment.